Analysis of the Abbott BinaxNOW fast antigen check for SARS-CoV-2 an infection in kids: Implications for screening in a faculty setting
Background: Speedy antigen assessments maintain a lot promise to be used within the faculty setting. Nonetheless, the efficiency of those assessments in non-clinical settings and amongst one of many predominant goal populations in schools-asymptomatic children-is unclear. To handle this hole, we examined the optimistic and unfavourable concordance between the BinaxNOW™ fast SARS-CoV-2 antigen assay and an RT-PCR check amongst kids at a community-based Covid-19 testing web site.
Strategies: We performed fast antigen (BinaxNOW™) and oral fluid RT-PCR (Healing Labs) assessments on kids presenting at a walk-up testing web site in Los Angeles County from November 25, 2020 to December 9, 2020. Constructive concordance was decided because the fraction of RT-PCR optimistic individuals that had been additionally antigen optimistic. Unfavorable concordance was decided because the fraction of RT-PCR unfavourable individuals that had been additionally antigen unfavourable. Multivariate logistic regression fashions had been used to look at the affiliation between optimistic or unfavourable concordance and participant age, race-ethnicity, intercourse at start, signs and Ct values.
Outcomes: 226 kids examined optimistic on RT-PCR; 127 kids or 56.2% (95% CI: 49.5% to 62.8%) of those additionally examined optimistic on the fast antigen check. Constructive concordance was larger amongst symptomatic kids (64.4%; 95% CI: 53.4% to 74.4%) in comparison with asymptomatic kids (51.1%; 95% CI: 42.5% to 59.7%). Constructive concordance was negatively related to Ct values and was 93.8% (95% CI: 69.8% to 99.8%) for kids with Ct values lower than or equal to 25. 548 kids examined unfavourable on RT-PCR; 539 or 98.4% (95% CI: 96.9% to 99.2%) of those additionally examined unfavourable on the fast antigen check. Unfavorable concordance was larger amongst asymptomatic kids.
Conclusions: Speedy antigen testing can efficiently establish most COVID infections in kids with viral load ranges prone to be infectious. Serial fast testing might assist compensate for restricted sensitivity in early an infection

tissue-bank
H. pylori Ag Rapid Test External Control Kit |
C0192 |
CTK Biotech |
each |
EUR 560 |
|
Helicobacter Pylori Antibody (Anti-HP) Rapid Test Kit |
abx092204-100l |
Abbexa |
100 µl |
EUR 650 |
Helicobacter Pylori Antibody (Anti-HP) Rapid Test Kit |
abx092204-1ml |
Abbexa |
1 ml |
EUR 7200 |
Helicobacter Pylori Antibody (Anti-HP) Rapid Test Kit |
abx092204-200l |
Abbexa |
200 µl |
EUR 2100 |
Human Helicobacter Pylori (HP) IgG Rapid Test Kit |
abx092090-20tests |
Abbexa |
20 tests |
EUR 276 |
|
Human Helicobacter Pylori IgG (HP IgG) Rapid Test Kit |
abx092090-100l |
Abbexa |
100 µl |
EUR 225 |
Human Helicobacter Pylori IgG (HP IgG) Rapid Test Kit |
abx092090-1ml |
Abbexa |
1 ml |
Ask for price |
Human Helicobacter Pylori IgG (HP IgG) Rapid Test Kit |
abx092090-200l |
Abbexa |
200 µl |
EUR 350 |
Brucella Antigen Rapid Test Kit |
abx092116-100l |
Abbexa |
100 µl |
EUR 350 |
Brucella Antigen Rapid Test Kit |
abx092116-1ml |
Abbexa |
1 ml |
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Brucella Antigen Rapid Test Kit |
abx092116-200l |
Abbexa |
200 µl |
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Rotavirus Antigen Rapid Test Kit |
abx092133-100l |
Abbexa |
100 µl |
EUR 362.5 |
Rotavirus Antigen Rapid Test Kit |
abx092133-1ml |
Abbexa |
1 ml |
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Rotavirus Antigen Rapid Test Kit |
abx092133-200l |
Abbexa |
200 µl |
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Norovirus Antigen Rapid Test Kit |
abx092261-100l |
Abbexa |
100 µl |
EUR 1925 |
Norovirus Antigen Rapid Test Kit |
abx092261-1ml |
Abbexa |
1 ml |
EUR 26250 |
Norovirus Antigen Rapid Test Kit |
abx092261-200l |
Abbexa |
200 µl |
EUR 6600 |
Rotavirus Antigen Rapid Test Kit |
abx092272-100l |
Abbexa |
100 µl |
EUR 362.5 |
Rotavirus Antigen Rapid Test Kit |
abx092272-1ml |
Abbexa |
1 ml |
Ask for price |
Rotavirus Antigen Rapid Test Kit |
abx092272-200l |
Abbexa |
200 µl |
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Helicobacter Pylori Antigen |
NAT41603-100 |
The Native Antigen Company |
0.1 |
EUR 395.28 |
|
Description: Bacteria are cultured on solid medium, harvested, washed and solubilised. The antigen is partially purified by detergent extraction and centrifugation. |
Helicobacter Pylori Antigen |
NAT41603-500 |
The Native Antigen Company |
0.5 |
EUR 1187.13 |
|
Description: Bacteria are cultured on solid medium, harvested, washed and solubilised. The antigen is partially purified by detergent extraction and centrifugation. |
Rabies Virus Antigen Rapid Test Kit |
abx092033-100l |
Abbexa |
100 µl |
EUR 375 |
Rabies Virus Antigen Rapid Test Kit |
abx092033-1ml |
Abbexa |
1 ml |
Ask for price |
Rabies Virus Antigen Rapid Test Kit |
abx092033-200l |
Abbexa |
200 µl |
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Human Rotavirus Antigen Rapid Test Kit |
abx472030-1096tests |
Abbexa |
10 × 96 tests |
Ask for price |
Human Rotavirus Antigen Rapid Test Kit |
abx472030-596tests |
Abbexa |
5 × 96 tests |
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Human Rotavirus Antigen Rapid Test Kit |
abx472030-96tests |
Abbexa |
96 tests |
EUR 237.5 |
Canine Parvovirus Antigen Rapid Test Kit |
abx092032-100l |
Abbexa |
100 µl |
EUR 375 |
Canine Parvovirus Antigen Rapid Test Kit |
abx092032-1ml |
Abbexa |
1 ml |
Ask for price |
Canine Parvovirus Antigen Rapid Test Kit |
abx092032-200l |
Abbexa |
200 µl |
Ask for price |
Canine Adenovirus Antigen Rapid Test Kit |
abx092138-100l |
Abbexa |
100 µl |
EUR 487.5 |
Canine Adenovirus Antigen Rapid Test Kit |
abx092138-1ml |
Abbexa |
1 ml |
Ask for price |
Canine Adenovirus Antigen Rapid Test Kit |
abx092138-200l |
Abbexa |
200 µl |
Ask for price |
Dog Toxoplasmosis Antigen Rapid Test Kit |
abx092277-100l |
Abbexa |
100 µl |
EUR 362.5 |
Dog Toxoplasmosis Antigen Rapid Test Kit |
abx092277-1ml |
Abbexa |
1 ml |
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Dog Toxoplasmosis Antigen Rapid Test Kit |
abx092277-200l |
Abbexa |
200 µl |
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Canine Coronavirus Antigen Rapid Test Kit |
abx092119-100l |
Abbexa |
100 µl |
EUR 325 |
Canine Coronavirus Antigen Rapid Test Kit |
abx092119-1ml |
Abbexa |
1 ml |
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Canine Coronavirus Antigen Rapid Test Kit |
abx092119-200l |
Abbexa |
200 µl |
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Feline Coronavirus Antigen Rapid Test Kit |
abx092135-100l |
Abbexa |
100 µl |
EUR 487.5 |
Feline Coronavirus Antigen Rapid Test Kit |
abx092135-1ml |
Abbexa |
1 ml |
Ask for price |
Feline Coronavirus Antigen Rapid Test Kit |
abx092135-200l |
Abbexa |
200 µl |
Ask for price |
Rapid Response COVID-19 Saliva Rapid Antigen Test |
BSV-COV-2C25B |
BioServUK |
25 tests |
EUR 316 |
Description: Rapid Response COVID-19 Saliva Rapid Antigen Test |
SARS-CoV-2 Antigen Rapid Test Kit |
CoV2Ag-1 |
UnScience |
1T |
EUR 9.6 |
|
Description: This kit adopts the sandwich method and the technical principle of colloidal gold immunochromatography to qualitative determine the SARS-CoV-2 antigen. During the test, the sample is dropped into the sample well, and chromatography is performed under the capillary effect. The SARS-CoV-2 antigen in the sample combined with the colloidal goldlabeled SARS-CoV-2 monoclonal antibody I, and then spread to the test area. It is captured by another coated antibody (SARS-CoV-2 monoclonal antibody II), to form a complex and gather in the test area (T line). The quality control area is coated with the goat antimouse antibody, and the colloidal gold-labeled antibody is captured to form a complex and aggregate in the quality control area (C line). If the C line does not show color, it indicates that the result is invalid, and this sample needs to be tested again. |
SARS-CoV-2 Antigen Rapid Test Kit |
CoV2Ag-25 |
UnScience |
25T/kit |
EUR 42 |
|
Description: This product is used for in vitro qualitative detection of SARS-CoV-2 antigen in human oropharyngeal swabs, nasal swabs and nasopharyngeal swabs. It is helpful as an aid in the screening of early mild, asymptomatic, or acute patients for identification of SARS-CoV-2 infection. |
SARS-CoV-2 Antigen Rapid Test Kit |
abx294181-100g |
Abbexa |
100 µg |
EUR 850 |
SARS-CoV-2 Antigen Rapid Test Kit |
abx294181-20g |
Abbexa |
20 µg |
EUR 100 |
SARS-CoV-2 Antigen Rapid Test Kit |
abx294181-50g |
Abbexa |
50 µg |
EUR 450 |
NOVATest Antigen Rapid Test Kit (For Single Use) (NOVA Test) |
nCov-500-01 |
Atlas Link Technology |
1T |
EUR 162 |
Dengue Virus NS1 Antigen Rapid Test Kit |
abx090706-100l |
Abbexa |
100 µl |
EUR 650 |
Dengue Virus NS1 Antigen Rapid Test Kit |
abx090706-1ml |
Abbexa |
1 ml |
EUR 7200 |
Dengue Virus NS1 Antigen Rapid Test Kit |
abx090706-200l |
Abbexa |
200 µl |
EUR 2100 |
Adenovirus Antigen and Rotavirus Antigen Rapid Test Kit |
abx090727-100l |
Abbexa |
100 µl |
EUR 775 |
Adenovirus Antigen and Rotavirus Antigen Rapid Test Kit |
abx090727-1ml |
Abbexa |
1 ml |
EUR 9000 |
Adenovirus Antigen and Rotavirus Antigen Rapid Test Kit |
abx090727-200l |
Abbexa |
200 µl |
EUR 2625 |
COVID-19 Antigen Rapid Test Pen (Saliva) |
BSV-COV-2PEN20 |
BioServUK |
20 pc |
EUR 177 |
Description: COVID-19 Antigen Rapid Test Pen (Saliva) |
Dengue Antigen for Rapid Test Recombinant |
rAP-5175 |
Angio Proteomie |
Inquiry |
Ask for price |
Helicobacter pylori Antigen Fluorescence Test Kit |
F11365 |
Ring Biotechnology Co |
15T |
EUR 40 |
Description: Feces, anal swabs |
Dog Giardia lamblia Antigen Rapid Test Kit |
abx092122-100l |
Abbexa |
100 µl |
EUR 487.5 |
Dog Giardia lamblia Antigen Rapid Test Kit |
abx092122-1ml |
Abbexa |
1 ml |
Ask for price |
Dog Giardia lamblia Antigen Rapid Test Kit |
abx092122-200l |
Abbexa |
200 µl |
Ask for price |
African Swine Fever Antigen Rapid Test Kit |
abx092160-100l |
Abbexa |
100 µl |
EUR 493.75 |
African Swine Fever Antigen Rapid Test Kit |
abx092160-1ml |
Abbexa |
1 ml |
Ask for price |
African Swine Fever Antigen Rapid Test Kit |
abx092160-200l |
Abbexa |
200 µl |
Ask for price |
GA COVID-19 Rapid Antigen Test |
BSV-3980 |
BioServUK |
20 tests |
EUR 500 |
Description: GA COVID-19 Rapid Antigen Test |
Avian Influenza Virus Antigen Rapid Test Kit |
abx092015-100l |
Abbexa |
100 µl |
EUR 343.75 |
Avian Influenza Virus Antigen Rapid Test Kit |
abx092015-1ml |
Abbexa |
1 ml |
Ask for price |
Avian Influenza Virus Antigen Rapid Test Kit |
abx092015-200l |
Abbexa |
200 µl |
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Feline Leukemia Virus Antigen Rapid Test Kit |
abx092134-100l |
Abbexa |
100 µl |
EUR 562.5 |
Feline Leukemia Virus Antigen Rapid Test Kit |
abx092134-1ml |
Abbexa |
1 ml |
Ask for price |
Feline Leukemia Virus Antigen Rapid Test Kit |
abx092134-200l |
Abbexa |
200 µl |
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Swine Influenza Virus Antigen Rapid Test Kit |
abx092159-100l |
Abbexa |
100 µl |
EUR 337.5 |
Swine Influenza Virus Antigen Rapid Test Kit |
abx092159-1ml |
Abbexa |
1 ml |
Ask for price |
Swine Influenza Virus Antigen Rapid Test Kit |
abx092159-200l |
Abbexa |
200 µl |
Ask for price |
Human Giardia lamblia Antigen Rapid Test Kit |
abx472016-1096tests |
Abbexa |
10 × 96 tests |
Ask for price |
Human Giardia lamblia Antigen Rapid Test Kit |
abx472016-596tests |
Abbexa |
5 × 96 tests |
Ask for price |
Human Giardia lamblia Antigen Rapid Test Kit |
abx472016-96tests |
Abbexa |
96 tests |
EUR 250 |
Canine Distemper Virus Antigen Rapid Test Kit |
abx092034-100l |
Abbexa |
100 µl |
EUR 375 |
Canine Distemper Virus Antigen Rapid Test Kit |
abx092034-1ml |
Abbexa |
1 ml |
Ask for price |
Canine Distemper Virus Antigen Rapid Test Kit |
abx092034-200l |
Abbexa |
200 µl |
Ask for price |
Canine Influenza Virus Antigen Rapid Test Kit |
abx092137-100l |
Abbexa |
100 µl |
EUR 362.5 |
Canine Influenza Virus Antigen Rapid Test Kit |
abx092137-1ml |
Abbexa |
1 ml |
Ask for price |
Canine Influenza Virus Antigen Rapid Test Kit |
abx092137-200l |
Abbexa |
200 µl |
Ask for price |
Feline Herpesvirus (FHV) Antigen Rapid Test Kit |
abx092275-100l |
Abbexa |
100 µl |
EUR 362.5 |
Feline Herpesvirus (FHV) Antigen Rapid Test Kit |
abx092275-1ml |
Abbexa |
1 ml |
Ask for price |
Feline Herpesvirus (FHV) Antigen Rapid Test Kit |
abx092275-200l |
Abbexa |
200 µl |
Ask for price |
Feline Calicivirus (FCV) Antigen Rapid Test Kit |
abx092279-100l |
Abbexa |
100 µl |
EUR 362.5 |
Feline Calicivirus (FCV) Antigen Rapid Test Kit |
abx092279-1ml |
Abbexa |
1 ml |
Ask for price |
Feline Calicivirus (FCV) Antigen Rapid Test Kit |
abx092279-200l |
Abbexa |
200 µl |
Ask for price |
Human Candida albicans Antigen Rapid Test Kit |
abx472009-1096tests |
Abbexa |
10 × 96 tests |
Ask for price |
Human Candida albicans Antigen Rapid Test Kit |
abx472009-596tests |
Abbexa |
5 × 96 tests |
Ask for price |
Human Candida albicans Antigen Rapid Test Kit |
abx472009-96tests |
Abbexa |
96 tests |
EUR 237.5 |
Dengue Epi-10 Antigen For Rapid Test |
MBS596126-1mg |
MyBiosource |
1mg |
EUR 360 |
Dengue Epi-10 Antigen For Rapid Test |
MBS596126-2mg |
MyBiosource |
2mg |
EUR 550 |
Dengue Epi-10 Antigen For Rapid Test |
MBS596126-5mg |
MyBiosource |
5mg |
EUR 1140 |
Dengue Epi-13 Antigen For Rapid Test |
MBS596127-1mg |
MyBiosource |
1mg |
EUR 360 |
Dengue Epi-13 Antigen For Rapid Test |
MBS596127-2mg |
MyBiosource |
2mg |
EUR 550 |
Dengue Epi-13 Antigen For Rapid Test |
MBS596127-5mg |
MyBiosource |
5mg |
EUR 1140 |
Dengue epi-10 antigen for rapid test |
MBS596210-1mg |
MyBiosource |
1mg |
EUR 360 |
Dengue epi-10 antigen for rapid test |
MBS596210-2mg |
MyBiosource |
2mg |
EUR 545 |
Dengue epi-10 antigen for rapid test |
MBS596210-5mg |
MyBiosource |
5mg |
EUR 1135 |
Dengue epi-13 antigen for rapid test |
MBS596211-1mg |
MyBiosource |
1mg |
EUR 360 |
Dengue epi-13 antigen for rapid test |
MBS596211-2mg |
MyBiosource |
2mg |
EUR 545 |
Dengue epi-13 antigen for rapid test |
MBS596211-5mg |
MyBiosource |
5mg |
EUR 1135 |
Newcastle Disease Virus Antigen Rapid Test Kit |
abx092016-100l |
Abbexa |
100 µl |
EUR 343.75 |
Newcastle Disease Virus Antigen Rapid Test Kit |
abx092016-1ml |
Abbexa |
1 ml |
Ask for price |
Newcastle Disease Virus Antigen Rapid Test Kit |
abx092016-200l |
Abbexa |
200 µl |
Ask for price |
Typhoid Antigen (S. typhi) Rapid Test Kit |
abx092222-100l |
Abbexa |
100 µl |
EUR 775 |
Typhoid Antigen (S. typhi) Rapid Test Kit |
abx092222-1ml |
Abbexa |
1 ml |
EUR 9000 |
Typhoid Antigen (S. typhi) Rapid Test Kit |
abx092222-200l |
Abbexa |
200 µl |
EUR 2625 |
Malaria PF and PV Antigen Rapid Test Kit |
abx092211-100l |
Abbexa |
100 µl |
EUR 775 |
Malaria PF and PV Antigen Rapid Test Kit |
abx092211-1ml |
Abbexa |
1 ml |
EUR 9000 |
Speedy Screening for Non-falciparum Malaria in Elimination Settings Utilizing Multiplex Antigen and Antibody Detection: Put up Hoc Identification of Plasmodium malariae in an Toddler in Haiti
Haiti is concentrating on malaria elimination by 2025. The Grand’Anse division in southwestern Haiti experiences one-third to half of all nationally reported Plasmodium falciparum instances. Though there are historic studies of Plasmodium vivax and Plasmodium malariae, immediately, non-falciparum infections would stay undetected due to in depth use of falciparum-specific histidine-rich protein 2 (HRP2) fast diagnostic assessments (RDT) at well being services. A latest case-control examine was performed in Grand’Anse to establish threat elements for P. falciparum an infection utilizing HRP2-based RDTs (n = 1,107).
Put up hoc multiplex Plasmodium antigenemia and antibody (IgG) detection by multiplex bead assay revealed one blood pattern optimistic for pan-Plasmodium aldolase, unfavourable for P. falciparum HRP2, and optimistic for IgG antibodies to P. malariae. Primarily based on this discovering, we chosen 52 samples with potential P. malariae an infection utilizing IgG and antigenemia information and confirmed an infection standing by species-specific PCR. We confirmed one P. malariae an infection in a 6-month-old toddler with out journey historical past.
Congenital P. malariae couldn’t be excluded. Nonetheless, our finding-in mixture with historic studies of P. malariae-warrants additional investigation into the presence and potential extent of non-falciparum malaria in Haiti. Moreover, we confirmed the usage of multiplex Plasmodium antigen and IgG detection in choosing samples of curiosity for subsequent PCR evaluation, thereby decreasing prices versus testing all out there samples by PCR. That is of particular use in low-transmission or eliminating settings the place infections are uncommon.
Speedy Antigen Detection Take a look at for Extreme Acute Respiratory Syndrome Coronavirus 2: How you can Use It Correctly?
Instances of coronavirus illness 2019 (COVID-19) in Indonesia are nonetheless rising and even larger in the previous few weeks. Contact tracing and surveillance are vital to find instances in the neighborhood, together with asymptomatic people. Analysis of COVID-19 relies upon on the detection of viral RNA, viral antigen, or not directly, viral antibodies. Molecular analysis, utilizing actual time, reverse transcriptase polymerase chain response (RT-PCR), is the frequent commonplace methodology; nonetheless, it isn’t extensively out there in Indonesia and requires a excessive commonplace laboratory.
Speedy, point-of-care antibody testing has been extensively used as a substitute; nonetheless, interpretation of the outcomes shouldn’t be easy and now it’s not utilized by the Indonesian authorities as a screening check for individuals travelling between areas. Thus, the fast antigen detection check (Ag-RDT) is utilized by the Indonesian authorities as a screening check for travellers. Because of this, many individuals purchase the package on-line and carry out self-Ag-RDT at residence.
This raises the query of how protected and correct it’s to carry out self-Ag-RDT at residence. Earlier than a check is utilized, it’s advised to analysis its sensitivity and specificity, as in comparison with gold commonplace, and its limitations. On this article, laboratory analysis of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mentioned, with an emphasis on Ag-RDT and the advice to make use of it correctly in each day observe.
Analysis of fast SARS-CoV-2 antigen assessments, AFIAS COVID-19 Ag and ichroma COVID-19 Ag, with serial nasopharyngeal specimens from COVID-19 sufferers
We evaluated the diagnostic accuracy of two newly developed, point-of-care, fast antigen assessments (RATs) for detecting SARS-CoV-2, the AFIAS COVID-19 Ag and the ichromaTM COVID-19 Ag, and investigated antigen kinetics. A complete of 200 serially collected nasopharyngeal (NP) specimens from 38 COVID-19 sufferers and 122 specimens from unfavourable controls had been analyzed. Diagnostic sensitivity and specificity had been assessed compared to molecular check outcomes and subdivided in line with focused genes (E, RdRP, and N) and days post-symptom onset (PSO). For the kinetics analysis, cut-off-indices from serial NP specimens had been used in line with the variety of days PSO.
Each RATs confirmed sensitivity of 91.3‒100% for specimens with cycle threshold (Ct) < 25. The specificity of AFIAS was 98.7‒98.9% and that of ichromaTM was 100.0%. The kappa values of AFIAS and ichromaTM for the molecular testing of specimens with Ct < 25 (RdRP) had been 0.97 and 1.00, respectively. The sensitivity of AFIAS and ichromaTM for all genes was decrease for specimens collected at 8‒14 PSO than for these collected earlier than 7-days PSO. The kinetics profiles confirmed that antigen ranges regularly decreased from ≤ 7-days PSO to > 22-days PSO. Each RATs confirmed glorious specificity and acceptable sensitivity for NP specimens with larger viral hundreds and for specimens collected inside 7-days PSO. Therefore, they’ve the potential to develop into helpful instruments for the early detection of SARS-CoV-2. Nonetheless, due to considerations about false negativity, RATs must be used together with molecular assessments.