Evaluation of the Abbott BinaxNOW rapid antigen test

Analysis of the Abbott BinaxNOW fast antigen check for SARS-CoV-2 an infection in kids: Implications for screening in a faculty setting 

Background: Speedy antigen assessments maintain a lot promise to be used within the faculty setting. Nonetheless, the efficiency of those assessments in non-clinical settings and amongst one of many predominant goal populations in schools-asymptomatic children-is unclear. To handle this hole, we examined the optimistic and unfavourable concordance between the BinaxNOW™ fast SARS-CoV-2 antigen assay and an RT-PCR check amongst kids at a community-based Covid-19 testing web site.

Strategies: We performed fast antigen (BinaxNOW™) and oral fluid RT-PCR (Healing Labs) assessments on kids presenting at a walk-up testing web site in Los Angeles County from November 25, 2020 to December 9, 2020. Constructive concordance was decided because the fraction of RT-PCR optimistic individuals that had been additionally antigen optimistic. Unfavorable concordance was decided because the fraction of RT-PCR unfavourable individuals that had been additionally antigen unfavourable. Multivariate logistic regression fashions had been used to look at the affiliation between optimistic or unfavourable concordance and participant age, race-ethnicity, intercourse at start, signs and Ct values.

Outcomes: 226 kids examined optimistic on RT-PCR; 127 kids or 56.2% (95% CI: 49.5% to 62.8%) of those additionally examined optimistic on the fast antigen check. Constructive concordance was larger amongst symptomatic kids (64.4%; 95% CI: 53.4% to 74.4%) in comparison with asymptomatic kids (51.1%; 95% CI: 42.5% to 59.7%). Constructive concordance was negatively related to Ct values and was 93.8% (95% CI: 69.8% to 99.8%) for kids with Ct values lower than or equal to 25. 548 kids examined unfavourable on RT-PCR; 539 or 98.4% (95% CI: 96.9% to 99.2%) of those additionally examined unfavourable on the fast antigen check. Unfavorable concordance was larger amongst asymptomatic kids.

Conclusions: Speedy antigen testing can efficiently establish most COVID infections in kids with viral load ranges prone to be infectious. Serial fast testing might assist compensate for restricted sensitivity in early an infection

SARS-CoV-2 Rapid Antigen Test Nasal
9901-NCOV-03G	Roche Diagnostics	25 Tests/Kit	EUR 94
Description: The SARS-CoV-2 Rapid Antigen Test is a lateral fl ow rapid chromatographic immunoassay for the qualitative detection of nucleocapsid antigen to SARS-CoV-2 present in human nasal samples. This test is intended for use as an aid in detection of SARS-CoV-2 infection in individuals suspected of COVID-19 with clinical symptoms onset within 5 days. Results are for the identification of SARS-CoV-2 nucleocapsid antigen. Antigen is generally detectable in human nasal swab samples during the acute phase of infection. Positive results indicate the presence of viral antigens, but clinical correlation with patient history and other diagnostic information is necessary to determine infection status. Positive results do not rule out bacterial infection or co- infection with other viruses. The agent detected may not be the definite cause of disease. Negative results should be treated as presumptive, and do not rule out SARS-CoV-2 infection and should not be used as the sole basis for treatment or patient management decisions, including infection control decisions. Negative results should be considered in the context of a patient’s recent exposures, history and the presence of clinical signs and symptoms consistent with COVID-19, and confirmed with a molecular assay, if necessary, for patient management. The SARS-CoV-2 Rapid Antigen Test is intended for use in laboratory or POC settings by healthcare professionals, or self-collection under the supervision of a healthcare worke

Human Streptococcus Pneumoniae (SP) Antigen Rapid Test Kit
abx092096-20tests	Abbexa	20 tests	EUR 398

Melamine Rapid Test Kit
abx092011-50tests	Abbexa	50 tests	EUR 370

NDV rapid test kit
RG15-03	Bionote	1 box	EUR 139.05
Description: Please check the datasheet of NDV rapid test kit before using the test.

IBD rapid test strip
RG15-04	Bionote	10 boxes	EUR 148
Description: Please check the datasheet of IBD rapid test strip before using the test.

Rabies rapid test strip
RG18-01	Bionote	10 boxes	EUR 151.92
Description: Please check the datasheet of Rabies rapid test strip before using the test.

Accu-Tell COVID-19 IgG/IgM Rapid Test
GEN-B352-20tests	Accu test	20 tests	EUR 236
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Accu-Tell COVID-19 IgG/IgM Rapid Test
GEN-B352-40tests	Accu test	40 tests	EUR 321
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Avian Influenza Virus Antigen Rapid Test Kit (Colloidal gold)
abx092015-40tests	Abbexa	40 tests	EUR 432

Newcastle Disease Virus Antigen Rapid Test Kit (Colloidal gold)
abx092016-40tests	Abbexa	40 tests	EUR 432

Human Chlamydia Trachomatis Antigen Rapid Test Kit (Colloidal gold)
abx092049-20tests	Abbexa	20 tests	EUR 230

Coronavirus (SARS-Cov-2) Antigen Rapid Test Device (Saliva)
IOV87952	INVBIO	20T/kit	EUR 39
Description: Coronavirus (SARS-Cov-2) Antigen Rapid Test Device (Saliva) is an in vitro diagnostic test for the qualitative detection of novel coronavirus antigens in human saliva, using the rapid immunochromatographic method. The identification is based on the monoclonal antibodies specific for the novel coronvirus antigen. It will provide information for clinical doctors to prescribe correct medications.

Melamine (MEL) Rapid Test Kit
abx092057-50tests	Abbexa	50 tests	EUR 370

Clenbuterol (CLE) Rapid Test Kit
abx092058-50tests	Abbexa	50 tests	EUR 244

Ractopamine (RAC) Rapid Test Kit
abx092059-50tests	Abbexa	50 tests	EUR 244

Salbutamol (SAL) Rapid Test Kit
abx092060-50tests	Abbexa	50 tests	EUR 244

Tetracycline (TCs) Rapid Test Kit
abx092063-50tests	Abbexa	50 tests	EUR 398

Sulfonamides (Sas) Rapid Test Kit
abx092064-40tests	Abbexa	40 tests	EUR 398

Quinolones (QNs) Rapid Test Kit
abx092065-40tests	Abbexa	40 tests	EUR 398

Ciprofloxacin (CPFX) Rapid Test Kit
abx092066-50tests	Abbexa	50 tests	EUR 398

Quinolones (QNs) Rapid Test Kit
abx092067-40tests	Abbexa	40 tests	EUR 398

Brucella Antibody Rapid Test Kit
abx092069-40tests	Abbexa	40 tests	EUR 356

Procalcitonin rapid test (Colloidal Gold)
abx095264-80Units	Abbexa	80 Units	EUR 954

Rapid Leishmania Ab Test Kit
RB2104	Bionote	1 box	EUR 127
Description: Please check the datasheet of Rapid Leishmania Ab Test Kit before using the test.

Rapid PED Ag Test Kit
RG14-01	Bionote	1 box	EUR 159.9
Description: Please check the datasheet of Rapid PED Ag Test Kit before using the test.

H, pylori CogA antigen 34 kDa
00347-V-01mg	Virogen	0,1 mg	EUR 267.5
Description: H. pylori CogA antigen 34 kDa

H, pylori CogA antigen 34 kDa
00347-V-1000ug	Virogen	1000 ug	EUR 1282.5
Description: H. pylori CogA antigen 34 kDa

Avian Influenza H5 Virus Antigen Rapid Test Kit (Colloidal gold)
abx092014-40tests	Abbexa	40 tests	EUR 488

Avian Influenza H7 Virus Antigen Rapid Test Kit (Colloidal gold)
abx092017-40tests	Abbexa	40 tests	EUR 432

Clenbuterol Rapid Test Kit (Colloidal gold)
abx092040-50tests	Abbexa	50 tests	EUR 272

Ractopamine Rapid Test Kit (Colloidal gold)
abx092042-50tests	Abbexa	50 tests	EUR 300

Salbutamol Rapid Test Kit (Colloidal gold)
abx092043-50tests	Abbexa	50 tests	EUR 342

Chloramphenicol Rapid Test Kit (Colloidal gold)
abx092045-50tests	Abbexa	50 tests	EUR 356

Quinolones Rapid Test Kit (Colloidal gold)
abx092046-50tests	Abbexa	50 tests	EUR 537

Sulfonamides Rapid Test Kit (Colloidal gold)
abx092047-50tests	Abbexa	50 tests	EUR 551

Tetracycline Rapid Test Kit (Colloidal gold)
abx092048-50tests	Abbexa	50 tests	EUR 467

Zearalenone Rapid Test Kit (Colloidal gold)
abx092051-50tests	Abbexa	50 tests	EUR 411

Deoxynivalenol Rapid Test Kit (Colloidal gold)
abx092052-50tests	Abbexa	50 tests	EUR 467

Deoxynivalenol Rapid Test Kit (Colloidal gold)
abx092053-50tests	Abbexa	50 tests	EUR 467

Aflatoxin Rapid Test Kit (Colloidal gold)
abx092054-50tests	Abbexa	50 tests	EUR 398

Zearalenone Rapid Test Kit (Colloidal gold)
abx092056-50tests	Abbexa	50 tests	EUR 425

Goat Brucella Antibody Rapid Test Kit
abx092070-40tests	Abbexa	40 tests	EUR 356

Cow Brucella Antibody Rapid Test Kit
abx092071-40tests	Abbexa	40 tests	EUR 356

Pig Parvovirus Antibody Rapid Test Kit
abx092074-50tests	Abbexa	50 tests	EUR 321

Fetal Fibronectin rapid test (Colloidal Gold)
abx095261-80Units	Abbexa	80 Units	EUR 1553

Anigen Rapid FIV Ab Test Kit
RB22-01-DD	Bionote	10 tests/Kit	EUR 129.8
Description: Please check the datasheet of Anigen Rapid FIV Ab Test Kit before using the test.

Rapid Bovine Brucella Ab Test Kit
RB23-01-DD	Bionote	1 kit/10 tests	EUR 151.79
Description: Please check the datasheet of Rapid Bovine Brucella Ab Test Kit before using the test.

Rapid Bovine TB Ab Test Kit
RB23-02-DD	Bionote	1 box	EUR 128.4
Description: Please check the datasheet of Rapid Bovine TB Ab Test Kit before using the test.

Rapid FMD NSP Ab Test Kit
RB28-02-DD	Bionote	1 box	EUR 135.4
Description: Please check the datasheet of Rapid FMD NSP Ab Test Kit before using the test.

Ag rapid CDV Ag Test Kit
RG11-03	Bionote	1 box	EUR 138.2
Description: Please check the datasheet of Ag rapid CDV Ag Test Kit before using the test.

Rapid TGE/PED Ag Test Kit
RG14-03	Bionote	1 box	EUR 240.85
Description: Please check the datasheet of Rapid TGE/PED Ag Test Kit before using the test.

Ag Rapid AIV Ag Test Kit
RG15-01	Bionote	1 box/30 tests	EUR 267
Description: Please check the datasheet of Ag Rapid AIV Ag Test Kit before using the test.

Ag Rapid H5AIV Ag test kit
RG15-05	Bionote	1 box	EUR 463
Description: Please check the datasheet of Ag Rapid H5AIV Ag test kit before using the test.

2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)
GEN-402-25tests	All test	25 tests	EUR 244
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

TruStrip RDT Anthrax Protective antigen 83 (PA83) Rapid Test cards, 25/pk
800-100-RDT-25	Alpha Diagnostics	1 pk	EUR 408

Furaltadone Metabolite Rapid Test Kit (Colloidal gold)
abx092035-50tests	Abbexa	50 tests	EUR 537

Furazolidone Metabolite Rapid Test Kit (Colloidal gold)
abx092036-50tests	Abbexa	50 tests	EUR 537

Aminohydantoin Hydrochloride Rapid Test Kit (Colloidal gold)
abx092037-50tests	Abbexa	50 tests	EUR 537

Nitrofurazone Metabolite Rapid Test Kit (Colloidal gold)
abx092038-50tests	Abbexa	50 tests	EUR 537

Malachite Green Rapid Test Kit (Colloidal gold)
abx092041-10tests	Abbexa	10 tests	EUR 300

Phenylethanolamine A Rapid Test Kit (Colloidal gold)
abx092044-50tests	Abbexa	50 tests	EUR 467

Aflatoxin B1 Rapid Test Kit (Colloidal gold)
abx092050-50tests	Abbexa	50 tests	EUR 370

Aflatoxin B1 Rapid Test Kit (Colloidal gold)
abx092055-50tests	Abbexa	50 tests	EUR 398

Human Echovirus (ECHO) IgM Rapid Test Kit
abx092093-20tests	Abbexa	20 tests	EUR 272

Human Toxoplasma (TOX) IgG Rapid Test Kit
abx092098-20tests	Abbexa	20 tests	EUR 217

Ag Rapid Bov. TB Ab Test Kit
RB23-02	Bionote	1 box	EUR 145
Description: Please check the datasheet of Ag Rapid Bov. TB Ab Test Kit before using the test.

Ag Rapid FMD NSP Ab Test Kit
RB28-02	Bionote	1 box	EUR 108.52
Description: Please check the datasheet of Ag Rapid FMD NSP Ab Test Kit before using the test.

Ag Rapid CIRD-3 Ag Test Kit
RG11-09	Bionote	1 box	EUR 123.64
Description: Please check the datasheet of Ag Rapid CIRD-3 Ag Test Kit before using the test.

Bionote Rapid AIV Ag_NDV Ag Test Kit
RG15-09	Bionote	1 box	EUR 164.52
Description: Please check the datasheet of Bionote Rapid AIV Ag_NDV Ag Test Kit before using the test.

COVID-19 IgG/IgM Rapid Test Kit
UNCOV-20	UnScience	20T/kit	EUR 155
Description: COVID-19 IgG/IgM Rapid Test (Serum/Plasma/Whole Blood) is a qualitative membrane-based immunoassay for the detection of COVID-19 antibodies in serum, plasma, or whole blood. This test consists of two test lines, an IgG line and an IgM line, which is pre-coated with two mouse anti-human monoclonal antibodies separately. During testing, the sample reacts with COVID-19 antigen-coated on conjugated pad. As the complex continues to travel up the strip, the anti-COVID-19 IgM antibodies are bound on the IgM line, and the anti-COVID-19 IgG antibodies are bound on the IgG line. The control(C)line appears when sample has flowed through the strip. The presence of anti-COVID-19 IgM and/or IgG will be indicated by a visible test line in the IgM and IgG region. To serve as a procedural control, the control line should always appear if the test procedure is performed properly and the reagents are working as intended.

Helicobacter pylori (H. pylori) Protein
abx061476-01ml	Abbexa	0.1 ml	EUR 551

Helicobacter pylori (H. pylori) Antibody
abx415714-1ml	Abbexa	1 ml	EUR 606

H. pylori Protein
abx069834-1mg	Abbexa	1 mg	EUR 1664

H. pylori Protein
abx069835-1mg	Abbexa	1 mg	EUR 787

NATtrol Zika Virus Stock (Qualitative) (1 mL)
TEST	Zeptometrix	1 mL	EUR 1106.64
Description: Please contact Gentaur in order to receive the datasheet of the product.

Helicobacter pylori (H. pylori) (flagellin) Antibody
abx023967-1mg	Abbexa	1 mg	EUR 662

Human Hepatitis A Virus IgG Rapid Test Kit
abx092012-25tests	Abbexa	25 tests	EUR 425

Pseudorabies Virus Antibodies Rapid Test Kit (Colloidal gold)
abx092026-50tests	Abbexa	50 tests	EUR 321

Canine Parvovirus Antibodies Rapid Test Kit (Colloidal gold)
abx092032-40tests	Abbexa	40 tests	EUR 356

Rabies Virus Antibodies Rapid Test Kit (Colloidal gold)
abx092033-40tests	Abbexa	40 tests	EUR 356

Clenbuterol-Ractopamine-Salbutamol Rapid Test Kit (Colloidal gold)
abx092039-40tests	Abbexa	40 tests	EUR 370

Cattle and Goat Hydatid Antibody Rapid Test Kit
abx092072-40tests	Abbexa	40 tests	EUR 356

Avian Influenza H5N1 Virus Antibody Rapid Test Kit
abx092075-40tests	Abbexa	40 tests	EUR 398

Human Chlamydia Pneumoniae (CP) IgG Rapid Test Kit
abx092079-20tests	Abbexa	20 tests	EUR 258

Human Chlamydia Pneumoniae (CP) IgM Rapid Test Kit
abx092080-20tests	Abbexa	20 tests	EUR 258

Human Mycoplasma Pneumoniae (MP) IgG Rapid Test Kit
abx092081-20tests	Abbexa	20 tests	EUR 258

Human Mycoplasma Pneumoniae (MP) IgM Rapid Test Kit
abx092082-20tests	Abbexa	20 tests	EUR 258

Human Mycobacterium Tuberculosis (MT) IgG Rapid Test Kit
abx092084-20tests	Abbexa	20 tests	EUR 230

Human Enterovirus 71 (EV71) IgM Rapid Test Kit
abx092091-20tests	Abbexa	20 tests	EUR 342

Human Hantavirus (HV) IgM / IgG Rapid Test Kit
abx092094-20tests	Abbexa	20 tests	EUR 272

Human Rubella Virus (RV) IgG Rapid Test Kit
abx092097-20tests	Abbexa	20 tests	EUR 217

Human Rabies Virus (HRV) IgG Rapid Test Kit
abx092100-20tests	Abbexa	20 tests	EUR 342

Speedy Screening for Non-falciparum Malaria in Elimination Settings Utilizing Multiplex Antigen and Antibody Detection: Put up Hoc Identification of Plasmodium malariae in an Toddler in Haiti 

Haiti is concentrating on malaria elimination by 2025. The Grand’Anse division in southwestern Haiti experiences one-third to half of all nationally reported Plasmodium falciparum instances. Though there are historic studies of Plasmodium vivax and Plasmodium malariae, immediately, non-falciparum infections would stay undetected due to in depth use of falciparum-specific histidine-rich protein 2 (HRP2) fast diagnostic assessments (RDT) at well being services. A latest case-control examine was performed in Grand’Anse to establish threat elements for P. falciparum an infection utilizing HRP2-based RDTs (n = 1,107).

Put up hoc multiplex Plasmodium antigenemia and antibody (IgG) detection by multiplex bead assay revealed one blood pattern optimistic for pan-Plasmodium aldolase, unfavourable for P. falciparum HRP2, and optimistic for IgG antibodies to P. malariae. Primarily based on this discovering, we chosen 52 samples with potential P. malariae an infection utilizing IgG and antigenemia information and confirmed an infection standing by species-specific PCR. We confirmed one P. malariae an infection in a 6-month-old toddler with out journey historical past.

Congenital P. malariae couldn’t be excluded. Nonetheless, our finding-in mixture with historic studies of P. malariae-warrants additional investigation into the presence and potential extent of non-falciparum malaria in Haiti. Moreover, we confirmed the usage of multiplex Plasmodium antigen and IgG detection in choosing samples of curiosity for subsequent PCR evaluation, thereby decreasing prices versus testing all out there samples by PCR. That is of particular use in low-transmission or eliminating settings the place infections are uncommon. 

Speedy Antigen Detection Take a look at for Extreme Acute Respiratory Syndrome Coronavirus 2: How you can Use It Correctly? 

Instances of coronavirus illness 2019 (COVID-19) in Indonesia are nonetheless rising and even larger in the previous few weeks. Contact tracing and surveillance are vital to find instances in the neighborhood, together with asymptomatic people. Analysis of COVID-19 relies upon on the detection of viral RNA, viral antigen, or not directly, viral antibodies. Molecular analysis, utilizing actual time, reverse transcriptase polymerase chain response (RT-PCR), is the frequent commonplace methodology; nonetheless, it isn’t extensively out there in Indonesia and requires a excessive commonplace laboratory.

Speedy, point-of-care antibody testing has been extensively used as a substitute; nonetheless, interpretation of the outcomes shouldn’t be easy and now it’s not utilized by the Indonesian authorities as a screening check for individuals travelling between areas. Thus, the fast antigen detection check (Ag-RDT) is utilized by the Indonesian authorities as a screening check for travellers. Because of this, many individuals purchase the package on-line and carry out self-Ag-RDT at residence.

This raises the query of how protected and correct it’s to carry out self-Ag-RDT at residence. Earlier than a check is utilized, it’s advised to analysis its sensitivity and specificity, as in comparison with gold commonplace, and its limitations. On this article, laboratory analysis of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mentioned, with an emphasis on Ag-RDT and the advice to make use of it correctly in each day observe.

Analysis of fast SARS-CoV-2 antigen assessments, AFIAS COVID-19 Ag and ichroma COVID-19 Ag, with serial nasopharyngeal specimens from COVID-19 sufferers 

We evaluated the diagnostic accuracy of two newly developed, point-of-care, fast antigen assessments (RATs) for detecting SARS-CoV-2, the AFIAS COVID-19 Ag and the ichromaTM COVID-19 Ag, and investigated antigen kinetics. A complete of 200 serially collected nasopharyngeal (NP) specimens from 38 COVID-19 sufferers and 122 specimens from unfavourable controls had been analyzed. Diagnostic sensitivity and specificity had been assessed compared to molecular check outcomes and subdivided in line with focused genes (E, RdRP, and N) and days post-symptom onset (PSO). For the kinetics analysis, cut-off-indices from serial NP specimens had been used in line with the variety of days PSO.

Each RATs confirmed sensitivity of 91.3‒100% for specimens with cycle threshold (Ct) < 25. The specificity of AFIAS was 98.7‒98.9% and that of ichromaTM was 100.0%. The kappa values of AFIAS and ichromaTM for the molecular testing of specimens with Ct < 25 (RdRP) had been 0.97 and 1.00, respectively. The sensitivity of AFIAS and ichromaTM for all genes was decrease for specimens collected at 8‒14 PSO than for these collected earlier than 7-days PSO. The kinetics profiles confirmed that antigen ranges regularly decreased from ≤ 7-days PSO to > 22-days PSO. Each RATs confirmed glorious specificity and acceptable sensitivity for NP specimens with larger viral hundreds and for specimens collected inside 7-days PSO. Therefore, they’ve the potential to develop into helpful instruments for the early detection of SARS-CoV-2. Nonetheless, due to considerations about false negativity, RATs must be used together with molecular assessments.